[Purpose/significance] From the perspective of users and designers, this article puts forward a new solving method based on Interpretive Structural Modeling (ISM), and does some research on the influential factors in promoting the mobile terminal application. [Method/process] During the research, by combining the SPSS statistical analysis method and the ISM, this article made up for the deficiency that ISM needed to judge the relations among various factors subjectively. [Result/conclusion] The results show that the hierarchy of the influence factors in APP promoting provides a better basis for effectively developing, applying and promoting the APP.