[Purpose/Significance] The study explored the relationship between scholars' scientific research cooperation and interdisciplinarity, in order to provide suggestions for scholars engaged in interdisciplinary research to improve their own cooperation modes, and evidence for optimizing cooperation strategies in the process of cultivating interdisciplinary talents. [Method/Process] Scholars are selected according to Price core author distribution theory. Based on Web of Science data, the study constructed the co-occurrence network of authors, used node degree centrality to measure the scale of cooperation, node clustering coefficient to measure the group cooperation rate, and proportion of international cooperation papers to measure the international cooperation rate; measured interdisciplinarity of scholars based on Rao-stirling. From the individual level, analyzed the relationship between scientific research cooperation and interdisciplinarity. [Result/Conclusion] Taking scholars in astrophysics as an example, the study found that the cooperation scale, group and international cooperation rate of scholars are significantly positively correlated with their interdisciplinarity. They are the factors that affect scholars' interdisciplinarity. And then infer that expansion of cooperation scale, participating in teamwork and international cooperation will all help them absorb more interdisciplinary knowledge, improve knowledge structure, and produce high-quality researches.