[Purpose/significance] Guided by the integration of theory and practice, it provided guidance for the realization of scene revolution, knowledge empowerment and practical path of enterprise knowledge management, and helped enterprise knowledge management to realize from 1 to N to N square. [Method/process] Through the scene revolution of the four dimensions of business field, knowledge field, interpersonal field and technology field, and applied the "1+4" model to make knowledge from "Management" to "Use", and finally interpreted the practice path of knowledge management in stages. [Result/Conclusion] Clarify the four dimensions of scene revolution and implement various scenarios; according to the "1+4" model, provide knowledge empowerment for knowledge assets, individuals, teams, organizations and businesses; comparing the path of practice, companies find their own development pain points, tailor-made knowledge management program, and provide better empowerment for enterprises and employees.